The role of science and research in overcoming the global crisis is very important, considering the challenges the world is currently facing, such as climate change, pandemics and the food crisis. In this context, science is a tool for understanding complex phenomena that affect human life and the environment. Research provides the data and evidence needed to make informed decisions. One of the main examples is in handling the COVID-19 pandemic, where scientific research has succeeded in accelerating the development of a safe and effective vaccine. Mass immunization backed by science not only helps reduce infection rates, but also provides hope for a return to normalcy. Additionally, epidemiological modeling produced by scientists allows governments and health organizations to formulate data-based policies to control the spread of the virus. On the other hand, climate change is a global challenge that requires a science-based approach. Research on greenhouse gas emissions and their impact on the environment has generated in-depth knowledge about climate behavior. With this understanding, countries can work together to reduce emissions through international agreements such as the Kyoto Protocol and the Paris Agreement. Renewable technology resulting from scientific research also provides solutions to reduce dependence on fossil energy sources. Science also plays an important role in the food crisis. Through biotechnology, scientists can develop plant varieties that are more resistant to pests and climate change. Research in the field of sustainable agriculture helps farmers to adopt more environmentally friendly practices, ensuring more efficient food production and reducing losses due to crop failure. Innovations such as hydroponics and vertical farming are examples of how science can create solutions to meet growing food needs. Furthermore, social science contributes to the understanding of the social and economic issues that often accompany global crises. Research on human behavior, migration patterns, and the social impact of economic injustice helps formulate more inclusive and equitable policies. By using an interdisciplinary approach involving natural and social sciences, more holistic solutions can be designed. International collaboration in research is also key to facing global challenges. Sharing data and resources between countries increases capabilities in research and supports innovation. Global initiatives such as the International Science Council and various international research institutions are coordinating efforts to collectively address these problems. By utilizing information and communication technology, data collection and analysis can be done more quickly and efficiently. The development of science-based applications to monitor the environment or public health further democratizes access to information, enabling individuals and communities to participate in solutions to the crises at hand. Investment in science education and research is also very important. Increasing human resource capacity in the field of science will prepare future generations to face more complex challenges. Therefore, encouraging interest in STEM (science, technology, engineering, and mathematics) fields from an early age should be a priority across the country. Science and research are important pillars in sustainable development and resolving global crises. Through proper understanding and innovation, positive change can be realized to create a safer and more sustainable world for all.